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You can easily screen your GFP transgenic experiments or search for novel fluorescent organisms with our simple, cost-effective flashlight. The NightSea BlueStar uses a high-intensity, very long life LED in combination with a custom interference filter to provide effective fluorescence excitation. The NightSea Filter Glasses block the reflected excitation light and pass only the fluorescence with high contrast.
Hundreds of research institutions around the world are using NightSea equipment with fluorescent proteins and other types of fluorescence research.
Success stories - just a few of many The research group of Prof. Stefan Offermanns, University of Heidelberg, is using the light to screen transgenic mouse embryos. A member of the group says "We have tried the GFP-lamp on mice embryos and it works perfectly. We could immediately select transgenic embryos without 2-days genetic analysis."
Dr. Merab Kokaia at Lund University Hospital in Sweden is successfully using the BlueStar and filter glasses to identify GFP in the retina of young adult transgenic mice (about 3-4 weeks old) by illuminating their eyes in the dark. It is no problem at all to distinguish them from wild-type mice.
Dr. Kerri Warren of Roger Williams University is using the BlueStar plus visor glasses to screen developing zebrafish that have been modified so that their vasculature is fluorescent. The flashlight enables her to rapidly check her specimens without having to put them under the fluorescence microscope. References - papers that cite the use of the NightSea GFP flashlight
Scott et al., 2010. A pathologic cascade leading to synaptic dysfunction in α-synuclein-induced neurodegeneration.
Journal of Neuroscience 30: 8083-8095.
Kawanami et al., 2009. Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum.
Biochemical and Biophysical Research Communications, 386: 477-482.
Wu et al., 2007. Toward simpler and faster genome-wide mutagenesis in mice.
Nature Genetics, 39(7): 922-930. Hou et al., 2007. Transgenic RNAi Depletion of Claudin-16 and the Renal Handling of Magnesium. J. Biol. Chem., 282(23): 17114-17122.
(If you know of any other references, please send us an e-mail) Specifications Battery: 3 C-cell
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